Esra Akbay, PhD, UT Southwestern Medical Center
Monica Guzman, PhD, Weill Cornell Medicine
Hilton Denver Inverness
200 Inverness Drive West
Englewood, CO 80112
Meeting #: Refer to your packet.
Hours: 8:00am – 8:00 pm EST M-F
International : 623-516-6140
Modern immunotherapy concepts have changed cancer treatment paradigms, such as immune checkpoint blockade, chimeric antigen receptor (CAR) T cells, and antibody-based therapies have made rapid progress in the past 10 years and are currently used to treat many cancers. Immune checkpoint inhibition circumvents tumor-induced suppression of cytotoxic T cell function. Adoptive transfer of T cells expressing chimeric antigen receptors (CARs) are currently approved treat CD19-positive cancers. However, only a fraction of patients responds, especially in the field of solid tumors as, for example, the immune microenvironment plays a critical role in disease progression and outcomes as it can induce immune suppressive signals that prevent immune-surveillance and allow malignant cells to persist. Therefore, combination treatments using different kind of immunotherapies targeting multiple checkpoints are necessary for more effective responses. Discussing all the components that are known to play a role in the mechanisms of immune escape and the emerging concepts for therapeutic interventions in a multidisciplinary setting will lead to the implementation of rationally designed trials to better harness immune system for the benefit of cancer patients.
Denver International Airport (DIA) is approximately 1 hour from the meeting location.
International participants are welcome to arrive on Wednesday to minimize chances for missed or delayed connections.
The abstracts should be only one or two paragraphs outlining the theme of your presentation and should reflect the objective and spirit of the meeting (see above). Abstracts will be circulated about one week before the meeting. The meeting organizer will start requesting them a month before the meeting.
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