Carla Grandori, MD, PhD, SEngine Precision Medicine
Christopher Kemp, PhD, Fred Hutchinson
The Inn at Ranchero Santa Fee
5951 Linea Del Cielo
Rancho Santa Fe, CA 92067
Meeting #: Refer to your packet.
Hours: 8:00am – 8:00 pm EST M-F
International : 623-516-6140
Two major roadblocks to improve cancer patient outcome are 1) the shortage of effective drugs and 2) the lack of precision in assigning existing drugs to patients. Most cancer drug development efforts focus on targeting a small number of genes that are commonly mutated in cancers such as activated oncogenes. However, these approaches have only benefited a small percentage of cancer patients, due to the inability to effectively target many mutated cancer genes and the overwhelming complexity of cancer genomes. An additional roadblock is that the model systems used most often in cancer research, cell lines and mouse models, do not sufficiently mimic any given patient’s cancer, so results obtained with these models often do not translate to clinical benefit.
Because these challenges are interrelated, an integrated approach is called for. This meeting will bring together a diverse panel of experts and thought leaders to share their ideas and discuss strategies to overcome these barriers toward achieving the goals of personalized medicine.
|Cheryl Arrowsmith, PhD||Princess Margaret Cancer Center|
|Jonathan B. Baell, PhD||Monash University|
|Rene Bernards, PhD||Netherlands Cancer Institute|
|Andrew Biankin, MD||University of Glasgow|
|Charles Boone, PhD||University of Toronto|
|Nyasha Chambwe, PhD||St. Jude Children's Research Hospital|
|Adrienne D. Cox, PhD||University of North Carolina at Chapel Hill|
|Mathew Garnett, PhD||Wellcome Sanger Institute|
|Carla Grandori, MD, PhD||SEngine Precision Medicine|
|Christopher Kemp, PhD||Fred Hutchinson Cancer Research Center|
|Christopher Lord||Institute of Cancer Research, London|
|Beverly Mock, PhD||National Institutes of Health|
|Michael Pishvaian||MD Anderson|
|Paul Workman||The Institute of Cancer Research|
|Michael Yaffe, MD, PhD||MIT|
|Brooke Emerling, PhD||Sanford Burnham Prebys Medical Discovery Institute|
|Andrew Venteicher, MD, PhD||University of Minnesota|
|Mark Zimmerman, PhD||Dana-Farber Cancer Institute|
San Diego International Airport (SAN) is approximately 30 minutes from the meeting location.
International participants are welcome to arrive on Wednesday to minimize chances for missed or delayed connections.
The abstracts should be only one or two paragraphs outlining the theme of your presentation and should reflect the objective and spirit of the meeting (see above). Abstracts will be circulated about one week before the meeting. The meeting organizer will start requesting them a month before the meeting.