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Tumor Microenvironment

November 1st - 4th, 2018

Chaired By

 Rakesh K. Jain, Ph.D., Massachusetts General Hospital
 Lisa M. Coussens, Ph.D., Knight Cancer Institute

Important Dates

 Complete - Acceptance
 08/01/2018 - Travel Form )
 10/15/2018 - Abstracts )

Venue Information

Hideaway Resort
3805 Walker Rd
Colorado Springs, CO 80908


Travel Agent Information

 Meeting #: Refer to your packet.
 Hours: 8:00am – 8:00 pm EST M-F
 Domestic: 669-210-8002
 International : 623-516-6140

About the Forbeck Foundation

 Forbeck Forum Information
 Travel Information
 General Program
 Frequently Asked Questions
 How to donate to this forum

Program Description

All cancers contain diverse populations of cells, including those harboring genetic mutations, aka "tumor" or "cancer" cells, as well as other "normal" cell types activated and/or recruited to local tumor microenvironments. Both preclinical and clinical data indicate that components of the tumor microenvironment (e.g., blood and lymphatic vessels, fibroblasts and other mesenchymal support cells, innate and adaptive immune cells, as well as extracellular matrix, hypoxia, and low pH), while regulating hallmark features of cancer development, can also thwart efficacy of cytotoxic, targeted and new- age immune therapies. This Forbeck Foundation meeting will bring together existing and emerging thought leaders spanning the breadth of tumor microenvironment, immune- oncology and computational biology disciplines to discuss novel approaches to identify critical mechanisms regulating crosstalk between neoplastic and "host" cells, with an emphasis on those that subvert anti-tumor immunity. We will also discuss therapeutic approaches to target aspects/components of the tumor microenvironment that effectively liberate anti-cancer immunity for durable tumor control, how these strategies are being deployed in patients, and initial clinical findings.

The 2018 Forum on Tumor Microenvironment will be chaired by Dr. Rakesh K. Jain of Massachusetts General Hospital and Harvard Medical School, and Dr. Lisa M Coussens from the Knight Cancer Institute at Oregon Health & Science University. The goal will be not only to discuss the current state of the tumor microenvironment field, but also discuss approaches towards applying that knowledge to the development of effective and broadly applicable anti- cancer therapies for long-term management of disease.

Participant Information

Participant Institution
Peter Carmeliet, MD, PhD Center for Cancer Biology, VIB-KU Leuven Belgium
Lisa Coussens, PhD Oregon Health & Science University
David G. DeNardo, PhD Washington University School of Medicine
Stephanie K. Dougan, PhD Dana-Farber Cancer Institute
Mikala Egeblad, Cold Spring Harbor Laboratory
Ronald N. Germain, MD, PhD NIAID, National Institute of Health
Richard O. Hynes, PhD Koch Institute for Integrative Cancer Research at MIT
Rakesh Jain, PhD Massachusetts General Hospital
Elaine R. Mardis, PhD Nationwide Children's Hospital
Daniela Quail, PhD McGill University
Melodie Swartz, PhD University of Chicago
David Tuveson, MD, PhD Cold Spring Harbor Laboratory
Matthew Vander Heiden, MD, PhD Koch Institute at MIT
Jennifer Wargo, MD MD Anderson Cancer Center
Irv Weissman, MD Stanford University

Airport Information

Denver International Airport (DIA) is approximately 1 hour from the meeting location.

  • Arrivals - Thursday at 3 PM, 5 PM and 7 PM
  • Departures -

Colorado Springs Airport (COS) is approximately 20 minutes from the meeting location.

  • Arrivals - Thursday at 3 PM
  • Departures -

International participants are welcome to arrive on Wednesday to minimize chances for missed or delayed connections.


The abstracts should be only one or two paragraphs outlining the theme of your presentation and should reflect the objective and spirit of the meeting (see above). Abstracts will be circulated about one week before the meeting. The meeting organizer will start requesting them a month before the meeting.